What Is Gefitinib?
Gefitinib is a small molecule, highly selective EGFR tyrosine kinase inhibitor (EGFR-TKI). It is primarily used for the treatment of non-small cell lung cancer (NSCLC) with activating EGFR mutations. Gefitinib functions as an EGFR inhibitor by selectively binding to the ATP-binding site of the EGFR tyrosine kinase domain. This binding prevents the autophosphorylation of...
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